Seroprevalencia de anticuerpos contra SARSCoV-2 entre adultos de un municipio del conurbano bonaerense, República Argentina

Abstract

Objective: determine the prevalence of anti-bodies against SARS-CoV-2. Method: between November twenty-one and December twelve of two thousand and twenty year, a cross-sectional study was carried out in 1182 samples from residents of a Buenos Aires town in the Province of Buenos Aires, Argentina. IgG was measured by ELISA in samples obtained by acupressure. Results: the global prevalence was 12.2 % (n = 144; 95 % CI: 10.3-14.0) with a ratio of 1: 3.8, between cumulative incidence and observational values. Prevalence in women and men were 13.0 % (95 % CI: 10.2-15.7) and 10.5 % (95 % CI: 7.6-13.3), respectively (p = 0.21). By age, the observed values were: 17.8 % (95 % CI: 12.0-23.6) in 18 and 30 years old group; 12.2 % (95 % CI: 9.3-15.1) in 31 to 60 years old group, 9.9 % (95 % CI: 6.9-13.9) in people over 61 years old (p = 0.02). According the socioeconomic tertiles (for Unsatisfied Basic Needs) the prevalence values were 7.7 % (95 % CI: 4.7-10.7) for Tertile I (best tertile), 12.5 % (95 % CI: 8.7-16.4) for Tertile II, and 15.2 % (95 % CI: 11.6-18.8) for Tertile III (p = 0.002). Conclusion: there were also differences between the neighbourhoods and between self-reported clinical variables. Specific IgM antibodies were detected in 12 samples, which represented 1% of the total. Seroprevalence studies provide useful information that can be apllied to fit modeling.